Standard sterilizable in place solutions

M series are standard SIP Fermenters/Bioreactors available in a range of six differt volumes volumes from 30 up to 200 litres with a wide range of options and accessories.
Benefits
- TK connection rather than TC ensures a better cleanibility and easier sterilization
- Re-sterilizable addition system (steam bridge): manual or automatic
- Manual and Automatic SIP (option) harvest and sampling valves
- Multiple sensors options pH, dO2, Redox, Total Cell density, Viable Cell density, Conductivity, dCO2
- Double jacket (side/bottom). Increased heat transfer efficiency. It ensures optimal temperature control and sterilization even at minimum volumes
- Top Powerful/ Accurate brushless motor, from 1 to 2000 RPM. Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth.
- Tri-Clamp stainless steel piping
- Peristaltic pumps: (selectable number) WM 114, WM 113, WM 520
- Different gas mixing strategies with up to 5 TMFC
- Automatic mechanical seal lubrication with steam condensate loop
- 19’’ coloured touch screen industrial HMI Leonardo: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes.
- N.2 heat exchangers and recirculating pump
- Separate drains, cooling return,condense to waste,hot condense return
- Gravimetric flow control (option): feed rates controlled through weight measurement
- Compact design
- CIP system options: removable spray balls or integrated system (recirculating pump + n.2 removable spray balls + software automation)
- Optional vessel empty sterilization
Modbus Digital sensors
Why a digital sensor?
Digital sensors (including Cell Density) has been integrated into Solaris PCS and Leonardo software giving the user the benefit of having a unique platform.
Fully compensated digital sensors, store and transmit all relevant sensor data, including calibration and diagnostic information directly to Solaris Leonardo software.
Wide range of choice between: pH, dO2, ORP, conductivity, Total Cell Density, Viable Cell Density.
Gas Mixing
Various controller and hardware configurations enable aeration strategies using air, oxygen, nitrogen or a mixture of these to enrich the air. The mass-flow controller allows the exact flow rate control of individual gases. The flexible aeration options integrated in the bioreactor permit a wide range of different application giving to this system a substantial versatility.

- Thermal Mass Flow Controller in entry model
- Gas mixing through TMFC+ solenoid valves or numbers of TMFC
- Automatic gas mixing algorithms for simplified controls (4-gas, 3-gas, O2 enrichment, N2 enrichment)
- Toro, fluted and sintered spargers
User-friendly Software
The software is the user’s best friend in experimental design planning and performing trial runs, as well as analyzing and optimizing media and parameters for cultivation.
The graphical user interface enables you to select the software functions intuitively. Data extracted are compatible with Windows Excel. However, Solaris has developed Leonardo data viewer, a platform where to easily and quickly manage fermentation data.
The software is included in the fermenter supply and can be installed on unlimited number of client’s PC or laptop.

