Pilot standard SIP fermenters / bioreactors

M SERIES

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The M series includes standard SIP fermenters/bioreactors available in a range of six different volumes from 30 up to 200 litres, with a wide range of options and accessories.

Solaris M SERIES

Features and benefits

6 different volumes: 30 L, 50 L, 75 L, 100 L, 150 L, 200 L.

3:1 H/D ratio.

Parts in contact with the culture AISI 316 L, other parts AISI 304.

Finishing: mirror polished (internal and external).

Compact design.

Double jacket (side/bottom), for higher heat transfer efficiency and optimal temperature control.

Bacteria (Toro sparger, Rushton impellers) and cell cultures (Sintered sparger, Marine impellers) configurations available.

Welded baffles.

Wide range of measurement and control options for cell cultures and aerobic/anaerobic microbial fermentations, including temperature, pH, dO2, dCO2, redox, antifoam, level, conductivity, weight, cell density (total cells, viable cells).

Modbus digital sensors.

Suitable for batch, fed-batch and continuous processes.

Stainless-steel industrial PCS LEM_2, with a selectable number of peristaltic pumps, choosing between Watson Marlow WM 114, WM 313 and WM 520.

Powerful and accurate (1 RPM) brushless motor, mounted on top.

Different gas mixing strategies with a selectable number of TMFCs or solenoid valves, for air, O2, CO2 and N2.

SALAS (Solaris Sterile Liquid Addition System) included in the standard configuration.

Up to 2 steam bridges (re-sterilizable diaphragm valves for inoculum/feedings) can be added in option (with manual or automatic sterilization control).

Non-SIP sampling and harvest valves are included in the standard configuration. Steam SIP lines can be added in option. Manual or automatic sterilization.

TK connection.

Tri-Clamp stainless steel piping.

Single mechanical seal. Double mechanical seal, with automatic lubrication though steam condensate loop available in option.

Thermoregulation loop consisting of n.2 heat exchangers and recirculating pump.

Separate drains: cooling water return, condense drain to waste, hot condense return.

Gravimetric flow control (option): feed rates controlled through weight measurement.

CIP system options: n. of removable spray balls or integrated system (recirculating pump + n. of removable spray balls + software automation). N. of spray balls depending on vessel volume.

Optional vessel empty sterilization.

Read the catalogue

Frequenty Asked Questions

Is it possible to perform sterile feeding?

Yes. In the M30, M50, and M75 models, the configuration with 1 steam bridge + 1 SALAS is available. Starting from the M100 model and above, it is possible to integrate up to 2 steam bridges + 1 SALAS.

Is sterile sampling possible?

Yes, it is possible. When configuring your bioreactor, you can choose between an automatic or a manual setup.

For which cultivations is the M-series suitable?

The M-series is suitable for both aerobic and anaerobic microbial cultivations, offering flexibility for different types of applications (one of the many fields of application can be agriculture

When scaling up, can I use the same sensors that I have in my benchtop bioreactor in the M-series?

Yes. The M-series allows you to maintain the same sensor configuration as in your benchtop bioreactor, ensuring consistency during scale-up.

In which industries can the M-series be applied?

Typical applications include biopharmaceuticals, biofuels, agriculture, bioremediation, bioplastics, cosmeceuticals, and nutraceuticals, making it a versatile platform for scale-up studies and small production runs.

Do you have a question?

Some features.

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Software

Innovative SCADA software LEONARDO 3.0: a smart and user-friendly controller designed to provide a high level of automated management of the fermentation/cultivation processes.
24” coloured touch screen industrial HMI.
Included in the equipment supply.
Data extraction in .csv format.
Remote access via PC, tablet or smartphone, with QR code scanning or dedicated portal.
Remote control for after sale assistance.

M Series can be
equipped with